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Genes or Proteins

The problem I am facing with current API queries in Open PHACTS is the lack of connection between protein target information (such as name, UniProt AC) and coding gene information (such as symbol, Entrez GeneID).

 

In the following cases this is problematic, nontrivial, or impossible:

  • Trying to list compounds against protein targets reported in DisGeNet as gene identifiers
  • Trying to find the gene symbols for a list of protein targets
  • Trying to find protein target expression levels in human tissues for a list of gene identifiers, e.g. from WikiPathways or DisGeNet or other

 

The information must be available in Open PHACTS, but I cannot get at it.

 

I use UniProt or NCBI webservices to help me out.

 

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